It's not so rosy for the Rossoneri after a damaging first-leg defeat to the black and blue side of Milan. Two goals in the first 15 minutes from Edin Dzeko and Henrikh Mkhitaryan shot Inter into a 2-0 lead. In response, they could only muster 13 shots, of which only two were on target.
Things have since gone from bad to worse for AC Milan - a meek 2-0 defeat to Spezia has left their top-four hopes in the balance and led to a dressing down in front of some angry ultras. After the game, footage of fans admonishing the players did the rounds on social media. They have also been struggling for firepower, managing just nine goals in their last 10 games in all competitions.
LeoVegas’ official partner Inter Milan, on the other hand, have won seven on the bounce in all competitions and have all but sewn up Champions League football for next season.
The last time the Nerazzurri won the Champions League was in 2010, as part of a memorable treble-winning campaign under the guidance of Jose Mourinho. They will have eyes on preventing a certain side in Manchester from replicating that feat should both teams make it to the final.
Currently, Inter are 27/25 to win the match with LeoVegas. Meanwhile, AC Milan are out at 11/4 to come out on top and 11/1 to get to the final.
It's round two at the San Siro in the Derby della Madonnina - but which side are you backing to make it through?
Last week's win over their fierce rivals means Inter have won four of the previous five clashes over AC Milan in all competitions. In the last three encounters, they have won each of them without conceding a goal.
Indeed, their defensive record of late looks very impressive on paper. On five occasions in the recent seven-game winning run, they kept a clean sheet.
All signs point to a low-scoring affair, which is why odds of 16/5 on Inter to win and under 2.5 goals looks like a good place to start with LeoVegas Sports!
Whether it's the finishing prowess of Romelu Lukaku or the experience of Dzeko, AC Milan defenders know they will be in for a rocky ride. We've earmarked the battle between Inter's frontline and Milan's defence as the critical point of interest.
Belgian international Lukaku will be keen to add to his tally of three for this season's Champions League and, at 39/20 at LeoVegas, he looks a good bet to get on the scoresheet whether starting or coming on as an impact substitute.
If the Rossoneri can keep Inter at bay, the return of Portuguese flying winger Rafael Leão from injury could provide them with the cutting edge they need to find a way through and make things awkward. He's only scored one goal in the competition this season but he does have three assists. You can get 4/1 on him to tee up a teammate with LeoVegas.
It could be a nervy clash, particularly given Inter's recent defensive strength and AC Milan's woes in front of goal. We are going with a low-scoring Inter win.
Bet Builder Top Tip: Inter Milan to win, AC Milan to score under 1.5 goals, Romelu Lukaku to score - 16/5.
*all odds correct at the time of writing and are subject to change